Discussion of consumer genomics, polygenic scores

I vibecoded a platform for analyzing consumer genomics data (whole genome sequences, and "SNP Chips" like those sold by 23andMe) => https://www.genewizard.net

It's currently free, and I'm looking for feedback! This session is not meant to be an advertisement for my company but more of a general discussion.

I'd be interested if people are actually finding consumer genomics services useful for improving their health, and what things people are most interested in learning about their genetics and risk.

About Gene Wizard:

Gene Wizard contains SNP pages that present information from scientific papers. These are meant to be a partial replacement for SNPedia, which stopped being updated in late 2019.

We also provide information on pharmacogenic SNPs, using open source star allele calling methods when possible.

Another rather unique thing we offer is polygenic scores from the https://www.pgscatalog.org,,although what I'm hearing from people is many of those scores perform poorly on independent validation sets.

I am also working a stand-alone app that people can use to calculate polygenic scores from their raw read data (ie .bam or .fasta). For technical reasons the polygenic scores calculated from the .bam, are more accurate than from .vcf. (see this blog post)\